Description

Tnf-α Inhibitor CAS NO 1049741-03-8 is a potent and selective small molecule compound designed to target and inhibit Tumor Necrosis Factor Alpha (TNF-α), a key cytokine involved in inflammatory pathways. This compound is critical for research and development in the life sciences sector, offering a valuable tool for studying inflammatory diseases and potential therapeutic interventions. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on immunology, autoimmune disorders, and drug discovery.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel anti-inflammatory and autoimmune disease therapeutics.
• Biochemical Assay Development: Used as a critical reagent in high-throughput screening (HTS) and in vitro assays to identify and validate new drug candidates targeting the TNF-α pathway.
• Academic & Preclinical Studies: Enables fundamental research into the mechanisms of inflammation, cytokine signaling, and the pathophysiology of conditions like rheumatoid arthritis, psoriasis, and inflammatory bowel disease.
• Cell Biology & Immunology: Applied in cell culture models to modulate TNF-α activity, allowing researchers to study cellular responses, apoptosis, and immune regulation.
• Drug Discovery Pipeline: Functions as a lead compound or a structural template for medicinal chemistry optimization programs aimed at creating new clinical candidates.

Basic Information

Product Name	Tnf-α Inhibitor
CAS No.	1049741-03-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	TNF-α Inhibitor; TNF Alpha Inhibitor; Tumor Necrosis Factor Alpha Inhibitor; Anti-TNF-α Compound; Small Molecule TNF-α Blocker; Immunomodulator Compound; Inflammatory Pathway Inhibitor; CAS 1049741-03-8
EINECS	Contact for details

Quality Control

Our Tnf-α Inhibitor is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. For short-term use, the material may be stored at 2-8°C. The compound is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.