Description

3-Cyano-4-(Trifluoromethyl)Benzoic Acid is a high-value, multi-functional aromatic building block characterized by its benzoic acid core substituted with both a cyano and a trifluoromethyl group. This unique structure makes it a critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs), where the trifluoromethyl group is prized for enhancing metabolic stability and lipophilicity. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in oncology, CNS, and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the CF3 group improves biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor for constructing polar components in electronic display materials and organic light-emitting diodes.
• Polymer Modification: Employed to introduce functional groups into polymer chains, altering physical properties for specialized coatings and engineering plastics.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions, amide bond formation, and cyclization processes to create complex molecular architectures.
• Chemical Research & Development: Essential for medicinal chemistry programs and material science research in academic and industrial laboratories.

Basic Information

Product Name	3-Cyano-4-(Trifluoromethyl)Benzoic Acid
CAS No.	1048034-95-2
Molecular Formula	C9H4F3NO2
Molecular Weight	215.13 g/mol
Synonyms	4-(Trifluoromethyl)-3-cyanobenzoic Acid; 3-Cyano-4-trifluoromethylbenzoic Acid; Benzoic acid, 3-cyano-4-(trifluoromethyl)-; 1048034-95-2; 3-CN-4-CF3-BA; 3-Cyano-α,α,α-trifluoro-p-toluic Acid
EINECS	Contact for details

Quality Control

Our production of 3-Cyano-4-(Trifluoromethyl)Benzoic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and compliance with customer specifications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The product should be kept away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.