Description

3-(2,4-Difluorophenyl)Butanoic Acid is a high-purity fluorinated organic building block of significant interest in advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where the difluorophenyl moiety can impart desirable metabolic stability and bioavailability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where fluorination enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving performance and stability.
• Organic Synthesis & Catalysis: Employed in cross-coupling reactions and as a substrate for developing new fluorination methodologies in academic and industrial research.
• Peptidomimetics & Bio-conjugates: The carboxylic acid functionality allows for coupling to create fluorinated amino acid analogs or linker molecules for bioconjugation.

Basic Information

Product Name	3-(2,4-Difluorophenyl)Butanoic Acid
CAS No.	1042815-69-9
Molecular Formula	C10H10F2O2
Molecular Weight	200.18 g/mol
Synonyms	3-(2,4-Difluorophenyl)butyric acid; 2,4-Difluoro-β-methylhydrocinnamic acid; Butanoic acid, 3-(2,4-difluorophenyl)-; 1042815-69-9; 3-(2,4-Difluorophenyl)butanoic acid; γ-(2,4-Difluorophenyl)butyric acid; 4-(2,4-Difluorophenyl)butanoic acid (registry number check advised)
EINECS	Contact for details

Quality Control

Our 3-(2,4-Difluorophenyl)Butanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure compliance with exacting customer specifications. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting cGMP and ISO 9001 standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.