Description

Peramivir Trihydrate is a potent neuraminidase inhibitor antiviral agent, specifically designed to combat influenza virus infections. Its primary value lies in its clinical efficacy for the treatment of acute, uncomplicated influenza in adults and children, offering a critical therapeutic option in global antiviral arsenals. This active pharmaceutical ingredient (API) is essential for pharmaceutical manufacturers engaged in the development and production of injectable antiviral medications, serving as a key component in pandemic preparedness and seasonal flu treatment strategies.

Application

• Active Pharmaceutical Ingredient (API) for the formulation of injectable antiviral drugs.
• Clinical Treatment of acute, uncomplicated influenza A and B virus infections.
• Pharmaceutical Research & Development for novel antiviral formulations and combination therapies.
• Reference Standard in analytical laboratories for quality control and method validation.
• Pandemic Preparedness Stockpiling for national and institutional health security.
• Bulk Drug Substance for contract manufacturing organizations (CMOs) specializing in sterile injectables.

Basic Information

Product Name	Peramivir Trihydrate
CAS No.	1041434-82-5
Molecular Formula	C15H28N4O4 • 3H2O
Molecular Weight	382.43 g/mol (Anhydrous basis: 328.41)
Synonyms	Peramivir; BCX-1812; RWJ-270201; (1S,2S,3R,4R)-3-[(1S)-1-Acetamido-2-ethylbutyl]-4-[(aminoiminomethyl)amino]-2-hydroxycyclopentanecarboxylic Acid Trihydrate; Rapivab (Brand Name); Peramivir Hydrate
EINECS	Contact for details

Quality Control

Our Peramivir Trihydrate is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and potency, aligning with ICH guidelines. A Certificate of Analysis (COA) detailing results for assay, related substances, residual solvents, and microbiological attributes is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under conditions that minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	12.0% - 15.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Microbiological Enumeration	Complies with Ph. Eur. 2.6.12/2.6.13

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.