Description

Methyl 2-Amino-4-Fluoro-5-Methylbenzoate is a high-purity fluorinated benzoate derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of amino and fluoro substituents on the aromatic ring, enabling precise molecular modifications for creating novel compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and specialty fine chemicals. The compound's specific structure facilitates the synthesis of complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-cancer agents, and anti-inflammatory medications.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and pesticides, where the fluorine atom enhances bioavailability and stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated organic semiconductors and charge-transport materials in display and lighting technologies.
• Fluorinated Dye & Pigment Development: Employed in creating specialized dyes and pigments with improved lightfastness and chemical resistance for high-performance applications.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Academic & Industrial R&D: Used in research laboratories for method development, catalysis studies, and exploring new chemical spaces in medicinal and materials chemistry.

Basic Information

Product Name	Methyl 2-Amino-4-Fluoro-5-Methylbenzoate
CAS No.	1037206-86-2
Molecular Formula	C9H10FNO2
Molecular Weight	183.18 g/mol
Synonyms	2-Amino-4-fluoro-5-methylbenzoic acid methyl ester; Methyl 2-amino-4-fluoro-5-methylbenzoate; Benzoic acid, 2-amino-4-fluoro-5-methyl-, methyl ester; 4-Fluoro-5-methylanthranilic acid methyl ester; Methyl 4-fluoro-5-methylanthranilate; 1037206-86-2; Methyl 2-amino-4-fluoro-5-methyl-benzoate
EINECS	Contact for details

Quality Control

Our production of Methyl 2-Amino-4-Fluoro-5-Methylbenzoate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure consistency and reliability. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our quality systems are designed to support cGMP compliance for pharmaceutical applications, and we welcome audits and specific quality agreements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.