Description

Ent-Oseltamivir Phosphate is a key pharmaceutical intermediate and stereoisomer of the antiviral drug oseltamivir phosphate. This compound is critical for research and development in the synthesis and study of neuraminidase inhibitors, providing essential insights into structure-activity relationships. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on antiviral drug development and process chemistry.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the research and development of antiviral active pharmaceutical ingredients (APIs).
• Chemical Reference Standard: Used as a high-purity standard in analytical methods development and validation for quality control laboratories.
• Stereochemical Studies: Essential for comparative studies on the biological activity and pharmacokinetics of oseltamivir stereoisomers.
• Process Chemistry R&D: Employed in route scouting, optimization, and scale-up studies for antiviral synthesis pathways.
• Academic Research: Utilized in university and institutional research projects focused on influenza virology and medicinal chemistry.
• Impurity Profiling: Acts as a known impurity or related substance standard in the HPLC analysis of oseltamivir phosphate batches.

Basic Information

Product Name	Ent-Oseltamivir Phosphate
CAS No.	1035895-89-6
Molecular Formula	C16H28N2O4 • H3PO4
Molecular Weight	410.36 g/mol (Free base: 312.41 g/mol)
Synonyms	(3R,4R,5S)-4-Acetamido-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylic Acid, Ethyl Ester, Phosphate Salt; (3R,4R,5S)-4-(Acetylamino)-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylic Acid Ethyl Ester Phosphate; Ro 64-0796/002; GS 4104; Enantiomer of Oseltamivir Phosphate; ent-Tamiflu Intermediate
EINECS	Contact for details

Quality Control

Our Ent-Oseltamivir Phosphate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identification by IR and NMR spectroscopy. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures material suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry conditions. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.