Description

4-Cyano-2,3-Difluorobenzoic Acid is a high-purity, multi-functional aromatic building block characterized by its benzoic acid core substituted with cyano and fluorine groups. This compound is valued for its role in facilitating structure-activity relationship (SAR) studies and enabling precise molecular modifications in advanced synthetic pathways. It is primarily sought by R&D and production teams in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides where the difluoro and cyano motifs enhance biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for designing specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of monomers for advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized as a building block for creating fluorescent tags, enzyme inhibitors, and other molecular probes for diagnostic applications.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-Cyano-2,3-Difluorobenzoic Acid
CAS No.	1033997-04-4
Molecular Formula	C8H3F2NO2
Molecular Weight	183.11 g/mol
Synonyms	2,3-Difluoro-4-cyanobenzoic Acid; Benzoic acid, 4-cyano-2,3-difluoro-; 4-Cyano-2,3-difluorobenzoic acid; 1033997-04-4
EINECS	Contact for details

Quality Control

Every batch of 4-Cyano-2,3-Difluorobenzoic Acid is manufactured under a strict quality management system. Our products undergo rigorous quality testing, including HPLC, NMR, and FTIR analysis, to ensure compliance with exacting customer specifications and industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.