Description

3-Bromo-n-tert-Butyl-4-Fluorobenzamide is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated benzamide structure. This compound is of significant value in modern organic synthesis, particularly for constructing complex molecules with specific steric and electronic properties. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in drug discovery and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of new active pharmaceutical ingredients (APIs), especially those targeting neurological disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the creation of novel herbicides and fungicides, where the fluorine and bromine substituents can enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals, contributing to the development of advanced materials with tailored properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and protein-ligand interactions in biochemical research.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes under cGMP conditions for clinical trial material production.

Basic Information

Product Name	3-Bromo-n-tert-Butyl-4-Fluorobenzamide
CAS No.	1033201-68-1
Molecular Formula	C11H13BrFNO
Molecular Weight	274.13 g/mol
Synonyms	3-Bromo-N-(tert-butyl)-4-fluorobenzamide; 4-Fluoro-3-bromo-N-tert-butylbenzamide; N-(tert-Butyl)-3-bromo-4-fluorobenzamide; 3-Bromo-4-fluoro-N-(1,1-dimethylethyl)benzamide; Benzamide, 3-bromo-N-(1,1-dimethylethyl)-4-fluoro-; 1033201-68-1; tert-Butyl 3-bromo-4-fluorobenzamide
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-n-tert-Butyl-4-Fluorobenzamide is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for demanding R&D and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.