Description

(2-Chloro-3,6-Difluorophenyl)Boronic Acid is a high-purity, multi-functional boronic acid derivative serving as a critical building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex biaryl structures.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific halogenated phenyl motifs.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of organic electronic materials, such as polymers for OLEDs and sensors.
• Ligand and Catalyst Development: Employed in the creation of novel palladium ligands and organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and inhibitors for biochemical and medicinal chemistry studies.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CROs/CMOs producing bespoke organic compounds for client projects.

Basic Information

Item	Details
Product Name	(2-Chloro-3,6-Difluorophenyl)Boronic Acid
CAS No.	1031226-45-5
Molecular Formula	C6H4BClF2O2
Molecular Weight	191.36 g/mol
Synonyms	2-Chloro-3,6-difluorophenylboronic acid; (2-Chloro-3,6-difluorophenyl)boronic acid; B-(2-Chloro-3,6-difluorophenyl)boronic acid; 2-Chloro-3,6-difluorobenzeneboronic acid; 1031226-45-5; Boronic acid, B-(2-chloro-3,6-difluorophenyl)-; AKOS025310647
EINECS	Contact for details

Quality Control

Our (2-Chloro-3,6-Difluorophenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.