Description

6-Bromo-2-Fluoro-3-(Trifluoromethyl)Benzoic Acid is a high-value, multi-functional aromatic building block characterized by its unique halogen and trifluoromethyl substitution pattern. This compound is essential for medicinal chemistry research and development, serving as a key intermediate in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D teams, agrochemical manufacturers, and advanced material scientists for constructing complex molecules with tailored properties.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine and bromine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the design of organic electronic materials, such as semiconductors and liquid crystals, due to its electron-withdrawing substituents.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific halogenated benzoic acid derivatives.

Basic Information

Product Name	6-Bromo-2-Fluoro-3-(Trifluoromethyl)Benzoic Acid
CAS No.	1026962-68-4
Molecular Formula	C8H3BrF4O2
Molecular Weight	287.01 g/mol
Synonyms	2-Fluoro-6-bromo-3-(trifluoromethyl)benzoic acid; 3-Trifluoromethyl-6-bromo-2-fluorobenzoic acid; Benzoic acid, 6-bromo-2-fluoro-3-(trifluoromethyl)-; 6-Bromo-2-fluoro-alpha,alpha,α-trifluoro-m-toluic acid
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-Fluoro-3-(Trifluoromethyl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.