Description

Benzoic Acid,1-(Difluoromethyl)-Methyl Ester is a specialized fluorinated organic compound that serves as a valuable building block in advanced chemical synthesis. Its unique structure, featuring a difluoromethyl group, makes it a critical intermediate for introducing fluorine atoms into target molecules, thereby enhancing their metabolic stability, lipophilicity, and bioavailability. This high-purity intermediate is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting central nervous system (CNS) disorders, anti-infectives, and oncology therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the difluoromethyl group can improve compound stability and efficacy.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and coatings with unique properties such as enhanced chemical resistance or low surface energy.
• Liquid Crystal & Electronic Chemicals: Potential intermediate in the synthesis of fluorinated compounds for electronic applications, including liquid crystal displays (LCDs) and dielectric materials.
• Organic Synthesis & Process Chemistry: A versatile reagent in academic and industrial laboratories for constructing complex fluorinated molecules, enabling structure-activity relationship (SAR) studies.

Basic Information

Product Name	Benzoic Acid,1-(Difluoromethyl)-Methyl Ester
CAS No.	1018678-48-2
Molecular Formula	C10H10F2O2
Molecular Weight	200.18 g/mol
Synonyms	Methyl 2-(Difluoromethyl)benzoate; 1-(Difluoromethyl)benzoic acid methyl ester; 2-(Difluoromethyl)benzoic Acid Methyl Ester; o-(Difluoromethyl)benzoic Acid Methyl Ester; Methyl o-(Difluoromethyl)benzoate; Benzoic acid, 2-(difluoromethyl)-, methyl ester; MFCD28499997
EINECS	Contact for details

Quality Control

Our Benzoic Acid,1-(Difluoromethyl)-Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for sensitive synthetic applications. Certificates of Analysis (COA) with detailed batch-specific results are provided to guarantee traceability and consistency for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.