Description

3-Ethoxy-2,4-Difluorobenzoic acid is a high-purity fluorinated benzoic acid derivative serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine and ethoxy substituents, which are essential for modulating the electronic properties, lipophilicity, and metabolic stability of target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS, anti-inflammatory, or anti-infective therapies.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the difluoro and ethoxy groups contribute to biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for display technologies, leveraging its aromatic core and fluorine atoms to influence mesomorphic properties.
• Organic Electronic Materials: Employed in the development of organic semiconductors, where its molecular structure can be integrated into polymers or small molecules for OLEDs or OFETs.
• Chemical Research & Development: A versatile reagent for exploring novel fluorination chemistry and constructing complex, multi-substituted aromatic scaffolds in academic and industrial labs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the scale-up and production of client-specific target molecules requiring this precise fluorinated benzoic acid motif.

Basic Information

Item	Details
Product Name	3-Ethoxy-2,4-Difluorobenzoic Acid
CAS No.	1017779-88-2
Molecular Formula	C9H8F2O3
Molecular Weight	202.16 g/mol
Synonyms	2,4-Difluoro-3-ethoxybenzoic Acid; Benzoic acid, 2,4-difluoro-3-ethoxy-; 3-Ethoxy-2,4-difluorobenzoic acid; 1017779-88-2; 2,4-Difluoro-3-ethoxybenzoicacid
EINECS	Contact for details

Quality Control

Our 3-Ethoxy-2,4-Difluorobenzoic acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing all specifications are available upon request, providing full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.