Description

1-[4-(Trifluoromethyl)Benzoyl]-1,4-Diazepane is a high-purity, advanced pharmaceutical intermediate characterized by its diazepane core and trifluoromethylbenzoyl moiety. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily utilized by pharmaceutical R&D laboratories, custom synthesis providers, and agrochemical innovators seeking to incorporate its unique structural features into new molecular entities.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, especially for neurological and psychiatric disorders.
• Agrochemical Research: Serves as a building block for developing new crop protection agents and herbicides with enhanced activity.
• Chemical Biology & Proteomics: Used as a molecular scaffold or ligand in the study of biological targets and enzyme inhibition.
• Material Science: Investigated for incorporation into specialty polymers or coatings to impart specific chemical resistance or surface properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and process development projects.
• Academic & Institutional Research: Utilized in university and government labs for medicinal chemistry programs and novel heterocyclic compound exploration.

Basic Information

Product Name	1-[4-(Trifluoromethyl)Benzoyl]-1,4-Diazepane
CAS No.	1016512-40-5
Molecular Formula	C14H15F3N2O
Molecular Weight	284.28 g/mol
Synonyms	1-[4-(Trifluoromethyl)benzoyl]-1,4-diazepane; 4-(Trifluoromethyl)benzoyl Homopiperazine; 1,4-Diazepane, 1-[[4-(trifluoromethyl)phenyl]carbonyl]-; Homopiperazine, 1-(4-trifluoromethylbenzoyl)-; 1-(4-Trifluoromethylbenzoyl)homopiperazine; 1-(4-(Trifluoromethyl)benzoyl)hexahydro-1,4-diazepine
EINECS	Contact for details

Quality Control

Our 1-[4-(Trifluoromethyl)Benzoyl]-1,4-Diazepane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.