Description

2-Fluoro-6-Iodophenylboronic Acid Pinacol Ester is a high-purity, multifunctional organoboron building block essential for modern synthetic chemistry. This compound is particularly valued for its stability and reactivity in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is a critical intermediate for researchers and manufacturers in pharmaceutical development, agrochemical synthesis, and advanced materials science, where precise functionalization is required.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and pesticides with specific targeting properties.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as OLEDs and semiconductors, where fluorinated and iodinated aromatics are advantageous.
• Chemical Biology Probes: Utilized to create tagged molecules and probes for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: An essential reagent for fine chemical suppliers and CROs/CMOs offering bespoke synthesis services.

Basic Information

Product Name	2-Fluoro-6-Iodophenylboronic Acid Pinacol Ester
CAS No.	1010839-66-3
Molecular Formula	C12H15BFO2I
Molecular Weight	347.96 g/mol
Synonyms	2-Fluoro-6-iodobenzeneboronic acid pinacol ester; (2-Fluoro-6-iodophenyl)boronic acid pinacol ester; 4,4,5,5-Tetramethyl-2-(2-fluoro-6-iodophenyl)-1,3,2-dioxaborolane; 2-(2-Fluoro-6-iodophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Boronic acid, B-(2-fluoro-6-iodophenyl)-, 1,1-dimethylethyl ester; Pinacol 2-Fluoro-6-iodophenylboronate
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-6-Iodophenylboronic Acid Pinacol Ester is produced and tested under strict quality management protocols to ensure consistent high purity and performance. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.