Description

3-[4-(Difluoromethoxy)Phenyl]Propionicacid is a high-purity, specialized organic intermediate featuring a difluoromethoxy-substituted phenylpropionic acid structure. This compound is valued for its role as a critical building block in the synthesis of advanced pharmaceutical and agrochemical agents, where its unique fluorine-containing moiety can significantly influence biological activity and metabolic stability. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for anti-inflammatory, analgesic, or metabolic disease targets.
• Agrochemical Synthesis: Serves as a crucial precursor for developing new-generation herbicides, fungicides, and insecticides, leveraging the difluoromethoxy group for enhanced efficacy and selectivity.
• Liquid Crystal & OLED Materials: Used in the synthesis of fluorine-containing aromatic compounds for electronic display materials and organic light-emitting diodes (OLEDs).
• Chemical Research & Development: Employed in academic and industrial labs for exploring new fluorination chemistry and creating proprietary compound libraries.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP conditions.

Basic Information

Product Name	3-[4-(Difluoromethoxy)Phenyl]Propionicacid
CAS No.	1000932-18-2
Molecular Formula	C10H10F2O3
Molecular Weight	216.18 g/mol
Synonyms	3-[4-(Difluoromethoxy)phenyl]propanoic acid; 4-(Difluoromethoxy)hydrocinnamic acid; 3-(4-(Difluoromethoxy)phenyl)propionic Acid; 1000932-18-2; Difluoromethoxy Phenyl Propionic Acid; DFMPPA; (4-(Difluoromethoxy)phenyl)propanoic acid
EINECS	Contact for details

Quality Control

Every batch of 3-[4-(Difluoromethoxy)Phenyl]Propionicacid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles via validated methods (HPLC, GC, NMR) is supplied with each shipment. Our quality commitment supports compliance in cGMP and ISO-guided environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.