Description

Methyl 3-Acetyl-4-Fluorobenzoate is a high-purity fluorinated aromatic ester, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in the strategic combination of the acetyl and fluorine functional groups, which are pivotal for constructing complex molecular architectures with tailored properties. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the development of fluorinated liquid crystals for high-performance displays (LCDs).
• Organic Electronics: Employed in the synthesis of fluorinated organic semiconductors and charge-transport materials for OLEDs and solar cells.
• Chemical Research: A versatile reagent for Suzuki-Miyaura and other cross-coupling reactions to create complex biaryl structures.
• Fluorine Chemistry Studies: Used as a model compound in academic and industrial research to study the effects of fluorine substitution on reactivity and physical properties.

Basic Information

Product Name	Methyl 3-Acetyl-4-Fluorobenzoate
CAS No.	198477-82-6
Molecular Formula	C10H9FO3
Molecular Weight	196.18 g/mol
Synonyms	Methyl 4-Fluoro-3-acetylbenzoate; 3-Acetyl-4-fluorobenzoic Acid Methyl Ester; 4-Fluoro-3-acetylbenzoic Acid Methyl Ester; Benzoic acid, 3-acetyl-4-fluoro-, methyl ester; Methyl (3-acetyl-4-fluorophenyl)formate
EINECS	Contact for details

Quality Control

Every batch of Methyl 3-Acetyl-4-Fluorobenzoate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency meet the exacting standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.