Description

Methyl 2-Fluoro-4-Hydroxybenzoate is a high-purity fluorinated benzoate ester derivative, serving as a critical building block in advanced organic synthesis. This compound is valued for its unique combination of a phenolic hydroxyl group and a fluorine substituent on the aromatic ring, which imparts specific electronic and steric properties to target molecules. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in oncology, CNS, and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators where the fluorine atom enhances bioactivity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated mesogens and electron-transport materials in display and lighting technologies.
• Polymer Modification: Incorporated as a monomer or additive to impart specific properties like UV stability, hydrophobicity, or chemical resistance to specialty polymers.
• Chemical Research & Development: Employed in academic and industrial labs for method development, catalysis studies, and exploring structure-activity relationships (SAR).
• Flavor & Fragrance Ingredient Synthesis: Acts as an intermediate for creating complex aromatic molecules with modified scent and taste profiles.

Basic Information

Product Name	Methyl 2-Fluoro-4-Hydroxybenzoate
CAS No.	197507-22-5
Molecular Formula	C8H7FO3
Molecular Weight	170.14 g/mol
Synonyms	2-Fluoro-4-hydroxybenzoic acid methyl ester; Methyl 2-fluoro-4-hydroxybenzoate; Methyl 4-hydroxy-2-fluorobenzoate; 4-Hydroxy-2-fluorobenzoic acid methyl ester; Benzoic acid, 2-fluoro-4-hydroxy-, methyl ester; 2-Fluoro-4-methoxycarbonylphenol
EINECS	Contact for details

Quality Control

Our Methyl 2-Fluoro-4-Hydroxybenzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the stringent requirements of our global clientele. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.