Description

Guanosine-13C,15N2 6-(o-Methyloxime) is a stable isotope-labeled derivative of guanosine, a fundamental nucleoside. This compound is critical for providing an internal standard in quantitative mass spectrometry, ensuring unparalleled accuracy and precision in analytical measurements. It is primarily required by researchers and quality control laboratories in the pharmaceutical, biotechnology, and diagnostic sectors for advanced metabolic studies, pharmacokinetic analysis, and the development of novel therapeutics.

Application

• Internal Standard for LC-MS/MS: Essential for the accurate quantification of guanosine and its metabolites in complex biological matrices like plasma, urine, and tissue homogenates.
• Metabolomics and Flux Analysis: Used in 13C and 15N tracer studies to investigate purine metabolism, nucleotide synthesis pathways, and cellular energy dynamics.
• Pharmaceutical R&D: Supports drug discovery and development by enabling precise measurement of drug-nucleotide interactions and metabolic stability.
• Diagnostic Assay Development: Serves as a key component in calibrating and validating high-sensitivity clinical diagnostic tests for metabolic disorders.
• Biochemical Research: A vital tool for enzymatic studies, exploring RNA synthesis, and understanding the role of guanosine in cellular signaling.
• Quality Control & Reference Material: Provides a certified reference material for ensuring the reliability and compliance of analytical methods in regulated environments.

Basic Information

Product Name	Guanosine-13C,15N2 6-(o-Methyloxime)
CAS No.	197228-02-7
Molecular Formula	C1113CH15N315N2O5
Molecular Weight	Contact for details
Synonyms	Guanosine-13C,15N2 6-(O-Methyloxime); [13C,15N2]-Guanosine 6-(O-Methyloxime); 6-(O-Methyloxime)-guanosine-13C,15N2; Isotopically Labeled Guanosine Oxime; 9-β-D-Ribofuranosylguanine-13C,15N2 6-(O-Methyloxime); Stable Isotope-Labeled Guanosine Derivative; Guanosine (6-O-methyloxime)-13C,15N2
EINECS	Contact for details

Quality Control

Every batch of our Guanosine-13C,15N2 6-(o-Methyloxime) is manufactured and analyzed under strict quality systems. We guarantee high chemical and isotopic purity, with comprehensive testing performed using advanced techniques including NMR, HPLC, and mass spectrometry. Certificates of Analysis (COA) are provided, detailing batch-specific data for isotopic enrichment, chemical purity, and identity confirmation to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Enrichment	≥ 99 atom % 13C; ≥ 99 atom % 15N
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, Methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.