Description

2,6-Difluoro-4-Nitro-Benzoic Acid is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active ingredients, specialty dyes, and advanced materials who require reliable access to high-quality, well-characterized intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules containing fluorinated aromatic rings, which are prevalent in modern drug discovery.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, where the difluoro-nitro-benzoic acid scaffold contributes to biological activity and metabolic stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated organic semiconductors and liquid crystal compounds, enhancing electronic properties and stability.
• Dyestuff & Pigment Intermediate: Employed in the production of specialized, high-performance dyes and pigments where nitro and carboxylic acid groups allow for further functionalization.
• Cross-Coupling Reactions: The carboxylic acid and halogen substituents make it a versatile substrate for Suzuki, Sonogashira, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D focused on fluorochemistry, nitroaromatic chemistry, and the development of new synthetic methodologies.

Basic Information

Product Name	2,6-Difluoro-4-Nitro-Benzoic Acid
CAS No.	196194-57-7
Molecular Formula	C7H3F2NO4
Molecular Weight	203.10 g/mol
Synonyms	4-Nitro-2,6-difluorobenzoic Acid; 2,6-Difluoro-4-nitrobenzoic Acid; Benzoic acid, 2,6-difluoro-4-nitro-; 2,6-Difluoro-4-nitro-benzoic acid; 196194-57-7; 4-Nitro-2,6-difluorobenzoic acid; Difluoronitrobenzoic acid
EINECS	Contact for details

Quality Control

Every batch of 2,6-Difluoro-4-Nitro-Benzoic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, and custom specifications can be developed to support your specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases, reducing agents, and sources of ignition. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.