Description

5-Hydroxy Isatoic Anhydride is a specialized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its bifunctional reactivity, serving as a versatile precursor for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This compound is essential for chemists and R&D teams developing active pharmaceutical ingredients (APIs), fine chemicals, and high-performance materials where precise molecular modification is required.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those with heterocyclic cores, such as quinazolinones and benzodiazepines.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that require specific isatoic anhydride derivatives.
• Dye and Pigment Chemistry: Serves as a precursor for creating specialized chromophores and fluorescent markers due to its aromatic and anhydride structure.
• Polymer Modification: Employed to introduce reactive sites or functional groups into polymer chains to alter material properties like adhesion or thermal stability.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological processes and enzyme activity.
• Academic & Industrial R&D: A fundamental research chemical for exploring new organic reactions and catalytic processes in synthetic chemistry.

Basic Information

Product Name	5-Hydroxy Isatoic Anhydride
CAS No.	195986-91-5
Molecular Formula	C8H5NO4
Molecular Weight	179.13 g/mol
Synonyms	5-Hydroxy-1H-benzo[d][1,3]oxazine-2,4-dione; 5-Hydroxy-2H-3,1-benzoxazine-2,4(1H)-dione; 5-Hydroxy-1,3-dihydro-2H-3,1-benzoxazine-2,4-dione; 5-Hydroxyisatoic Anhydride; 5-Hydroxy-2,4-dioxo-1,3-dihydro-2H-3,1-benzoxazine; 5-Hydroxy-1H-3,1-benzoxazine-2,4-dione; 5-Hydroxy-2,4(1H,3H)-benzoxazinedione
EINECS	Contact for details

Quality Control

Our 5-Hydroxy Isatoic Anhydride is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.