Description

3',5'-Di-(Trifluoromethyl)-Biphenyl-4-Carboxylic Acid is a high-value, multi-functional aromatic carboxylic acid building block distinguished by its biphenyl core and strategically positioned trifluoromethyl groups. This compound is essential for advanced synthesis, where its unique structure imparts desirable properties like enhanced lipophilicity, metabolic stability, and electronic effects to target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in oncology, central nervous system (CNS), and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for constructing complex organic molecules used in electronic displays and optoelectronic devices due to its rigid, fluorinated aromatic system.
• Catalyst & Ligand Development: Employed in the synthesis of specialized ligands for transition metal catalysis, enabling novel synthetic transformations.
• Polymer Modification: Incorporated as a monomer or additive to engineer polymers with specific thermal, chemical, or surface properties.
• Chemical Research & Development: A versatile building block for exploring new chemical spaces in medicinal chemistry and material science.

Basic Information

Product Name	3',5'-Di-(Trifluoromethyl)-Biphenyl-4-Carboxylic Acid
CAS No.	195457-74-0
Molecular Formula	C15H8F6O2
Molecular Weight	334.22 g/mol
Synonyms	4'-(3,5-Bis(trifluoromethyl)phenyl)biphenyl-4-carboxylic acid; [1,1'-Biphenyl]-4-carboxylic acid, 3',5'-bis(trifluoromethyl)-; 3',5'-Bis(trifluoromethyl)biphenyl-4-carboxylic acid; 3,5-Bis(trifluoromethyl)-[1,1'-biphenyl]-4-carboxylic acid; 4-Carboxy-3',5'-bis(trifluoromethyl)biphenyl
EINECS	Contact for details

Quality Control

Our production of 3',5'-Di-(Trifluoromethyl)-Biphenyl-4-Carboxylic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.