Description

8 - Azoniabicyclo[3.2.1]Oct - 6 - Ene, 3 - [(2 - Hydroxy - 2,2 - Di - 2 - Thienylacetyl)Oxy] - 8,8 - Dimethyl - , Bromide is a complex quaternary ammonium salt derivative of a tropane alkaloid structure, serving as a key advanced pharmaceutical intermediate. This compound is critical for its role in the synthesis of active pharmaceutical ingredients (APIs) targeting the central nervous system. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development and production of specialized therapeutics.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel tropane-based active pharmaceutical ingredients (APIs).
• Neurological Research: Used in preclinical and clinical research for developing compounds that interact with cholinergic and other neurotransmitter systems.
• Medicinal Chemistry: Serves as a sophisticated scaffold for structure-activity relationship (SAR) studies and drug discovery programs.
• GMP Manufacturing: Employed in the cGMP-compliant production of controlled substances for therapeutic use.
• Reference Standard: Can be utilized as a high-purity analytical reference standard for quality control and regulatory submissions.

Basic Information

Product Name	8 - Azoniabicyclo[3.2.1]Oct - 6 - Ene, 3 - [(2 - Hydroxy - 2,2 - Di - 2 - Thienylacetyl)Oxy] - 8,8 - Dimethyl - , Bromide
CAS No.	194222-44-1
Molecular Formula	C19H24BrNO3S2
Molecular Weight	458.43 g/mol
Synonyms	8-Azoniabicyclo[3.2.1]oct-6-ene, 3-[(2-hydroxy-2,2-di-2-thienylacetyl)oxy]-8,8-dimethyl-, bromide; 3-Tropanyl 2-Hydroxy-2,2-di(thiophen-2-yl)acetate Methobromide; Tropanyl 2-Hydroxy-2,2-di(2-thienyl)acetate Methobromide; 8-Methyl-8-azabicyclo[3.2.1]oct-6-en-3-yl 2-hydroxy-2,2-di(thiophen-2-yl)acetate methobromide; Tropane derivative bromide salt; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our 8 - Azoniabicyclo[3.2.1]Oct - 6 - Ene, 3 - [(2 - Hydroxy - 2,2 - Di - 2 - Thienylacetyl)Oxy] - 8,8 - Dimethyl - , Bromide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance with cGMP and other regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Long-term storage under inert atmosphere is recommended.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.