Description

Ganciclovir Monoproprionate is a key pharmaceutical intermediate and prodrug form of the potent antiviral agent ganciclovir. This compound is critical for enhancing the bioavailability and targeted delivery of the active drug, making it a vital component in advanced antiviral therapy development. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the synthesis of antiviral medications, particularly for the treatment of cytomegalovirus (CMV) infections and related conditions.

Application

• Pharmaceutical Intermediate: Primary use in the synthesis of ganciclovir and its related prodrug formulations for enhanced therapeutic efficacy.
• Antiviral Drug Development: Serves as a crucial building block in R&D for novel antiviral agents targeting herpesviruses, including CMV, HSV-1, and HSV-2.
• Prodrug Synthesis: Used to create more bioavailable and patient-compliant oral dosage forms of ganciclovir.
• Active Pharmaceutical Ingredient (API) Manufacturing: An essential raw material in the cGMP production of finished antiviral drugs.
• Biochemical Research: Employed in virology and molecular biology studies to investigate viral replication mechanisms and inhibition.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for drug testing and validation.

Basic Information

Product Name	Ganciclovir Monoproprionate
CAS No.	194159-18-7
Molecular Formula	C14H21N5O5
Molecular Weight	339.35 g/mol
Synonyms	Ganciclovir Monopropionate; 9-[(1,3-Dihydroxy-2-propoxy)methyl]guanine Monopropionate; 2-Amino-1,9-dihydro-9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-6H-purin-6-one Monopropionate; Ganciclovir Propionate; GCV Monopropionate; DHPG Monopropionate; BW759U Monopropionate; Cytovene Intermediate
EINECS	Contact for details

Quality Control

Our Ganciclovir Monoproprionate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and stringent control of residual solvents and impurities. Certificates of Analysis (COA) are provided, detailing compliance with in-house specifications developed for pharmaceutical intermediate applications. We support audits and can provide documentation for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.