Description

Alamifovir is a potent antiviral nucleoside analog with significant research and development interest. This compound is a key intermediate and reference standard for the synthesis and analysis of novel antiviral pharmaceuticals. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and manufacturers of active pharmaceutical ingredients (APIs) focused on antiviral therapies.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of advanced antiviral drug candidates.
• Reference Standard: Used for analytical method development, validation, and quality control (QC) testing in pharmaceutical manufacturing.
• Biochemical Research: Employed in in vitro studies to investigate mechanisms of action against viral replication.
• Antiviral Drug Development: A key material for R&D programs targeting the development of new treatments for viral infections.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the production scale-up of antiviral APIs under current Good Manufacturing Practices (cGMP).

Basic Information

Product Name	Alamifovir
CAS No.	193681-12-8
Molecular Formula	C8H12N5O4P
Molecular Weight	273.18 g/mol
Synonyms	1-[(2S,4R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-prop-1-ynylpyrimidine-2,4-dione; PMPA prodrug; (R)-9-[2-(Phosphonomethoxy)propyl]adenine cyclic 1',2'-propanyl ester; GS-7340 (developmental code); Alamifovir disoproxil (pro-drug form); Antiviral nucleoside phosphonate
EINECS	Contact for details

Quality Control

Our Alamifovir is manufactured and tested to meet high-purity standards suitable for pharmaceutical research and development. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality system is designed to support applications requiring reliable and consistent material performance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.