Description

(5Z,8Z,14Z)-11,12-Dihydroxyicosa-5,8,14-Trienoic Acid is a specialized dihydroxy fatty acid derivative, specifically a metabolite of arachidonic acid. This compound is of significant interest in biochemical and pharmacological research due to its role as a precursor to bioactive lipid mediators. It is primarily utilized by research institutions and pharmaceutical developers focused on inflammation, cell signaling pathways, and the development of novel therapeutic agents. CAS No. 192461-95-3.

Application

• Biochemical Research: Used as a high-purity reference standard and intermediate in the study of eicosanoid biosynthesis and metabolism.
• Pharmaceutical R&D: Serves as a critical precursor for the synthesis of specialized pro-resolving mediators (SPMs) and other lipid-based signaling molecules under investigation for therapeutic applications.
• Cell Biology Studies: Employed in in vitro and in vivo models to investigate the mechanisms of inflammation resolution and cellular communication.
• Analytical Standard: Essential for method development and calibration in analytical techniques like LC-MS and HPLC for the quantification of lipid metabolites in complex biological samples.

Basic Information

Product Name	(5Z,8Z,14Z)-11,12-Dihydroxyicosa-5,8,14-Trienoic Acid
CAS No.	192461-95-3
Molecular Formula	C₂₀H₃₄O₄
Molecular Weight	338.48 g/mol
Synonyms	11,12-DHET; 11,12-Dihydroxy-5Z,8Z,14Z-eicosatrienoic Acid; 11,12-Dihydroxyeicosatrienoic Acid; 11(12)-Epoxyeicosatrienoic Acid Diol; 11,12-DHETE; (±)11,12-DHET; 11,12-Dihydroxy-5,8,14-eicosatrienoic acid
EINECS	Contact for details

Quality Control

Our (5Z,8Z,14Z)-11,12-Dihydroxyicosa-5,8,14-Trienoic Acid is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. All materials are accompanied by comprehensive analytical documentation. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (HPLC/LC-MS)	Conforms to reference standard
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 0.5%
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.