Description

(R,R)-(-)-1,2-Diaminocyclohexane Hydrochloride is a high-purity chiral diamine salt, a crucial building block in asymmetric synthesis and catalysis. Its value lies in its ability to impart stereoselectivity in the production of complex pharmaceutical intermediates and fine chemicals. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require enantiomerically pure compounds for advanced applications.

Application

• Chiral Ligand Synthesis: A key precursor for the preparation of salen, phosphine, and other chiral ligands used in asymmetric catalysis.
• Pharmaceutical Intermediates: Employed in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and cardiovascular diseases.
• Asymmetric Catalysis: Used directly or as a derivative in metal-catalyzed asymmetric reactions, including hydrogenation, epoxidation, and Diels-Alder reactions.
• Resolution Agent: Acts as a resolving agent for the separation of racemic mixtures of carboxylic acids and other chiral compounds.
• Polymer Modification: Serves as a monomer or cross-linking agent for creating specialty polymers with specific chiral or chelating properties.
• Agrochemical Synthesis: Utilized in the production of chiral herbicides, fungicides, and plant growth regulators.

Basic Information

Product Name	(R,R)-(-)-1,2-Diaminocyclohexane Hydrochloride
CAS No.	191480-63-4
Molecular Formula	C6H14N2·HCl
Molecular Weight	150.65 g/mol
Synonyms	(1R,2R)-(-)-1,2-Diaminocyclohexane Monohydrochloride; (R,R)-1,2-DACH·HCl; (R,R)-(-)-trans-1,2-Diaminocyclohexane Hydrochloride; (1R,2R)-1,2-Diaminocyclohexane Hydrochloride; (R,R)-Cyclohexane-1,2-diamine Hydrochloride; (R,R)-DACH HCl; (R,R)-DACH·HCl; (1R,2R)-Cyclohexanediamine Hydrochloride
EINECS	Contact for details

Quality Control

Our (R,R)-(-)-1,2-Diaminocyclohexane Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific rotation is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Specific Rotation	-12.0° to -14.0° (c=1 in H2O)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.