Description

(S)-(-)-5,5-Diphenyl-4-(tert-Butyl)-2-Oxazolidinone is a high-purity, chiral oxazolidinone derivative widely used as a versatile chiral auxiliary and building block in asymmetric synthesis. Its value lies in enabling the stereoselective construction of complex molecules, which is critical for developing pharmaceuticals and advanced materials with high enantiomeric purity. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality chiral reagents.

Application

• Asymmetric Synthesis: Employed as a chiral auxiliary for the enantioselective alkylation, aldol, and Diels-Alder reactions.
• Pharmaceutical Intermediates: A key building block in the synthesis of active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Catalyst and Ligand Development: Used in the research and development of novel chiral catalysts and ligands for homogeneous catalysis.
• Agrochemical Synthesis: Facilitates the production of enantiomerically pure herbicides, fungicides, and insecticides.
• Academic & Industrial R&D: A valuable tool for methodological development in organic chemistry and process optimization.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, flavors, and fragrances where chirality impacts product performance.

Basic Information

Product Name	(S)-(-)-5,5-Diphenyl-4-(tert-Butyl)-2-Oxazolidinone
CAS No.	191090-36-5
Molecular Formula	C19H21NO2
Molecular Weight	295.38 g/mol
Synonyms	(S)-4-(tert-Butyl)-5,5-diphenyl-2-oxazolidinone; (S)-(-)-4-tert-Butyl-5,5-diphenyl-2-oxazolidinone; (S)-5,5-Diphenyl-4-(tert-butyl)oxazolidin-2-one; Evans Chiral Auxiliary Derivative; (S)-N-((tert-Butoxy)carbonyl)-α,α-diphenylglycinol Cyclic Derivative
EINECS	Contact for details

Quality Control

Our (S)-(-)-5,5-Diphenyl-4-(tert-Butyl)-2-Oxazolidinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.