Description

4-Carboxy-3,5-Dichlorobenzotrifluoride is a high-value trifluoromethylated aromatic building block, distinguished by its unique combination of carboxylic acid and halogen substituents. This compound is critical for the synthesis of advanced agrochemicals and pharmaceuticals, where its structure imparts desirable biological activity and metabolic stability. It is primarily sought by R&D chemists and process development scientists in the fine chemical and life science industries for creating novel active ingredients and functional materials.

Application

• Agrochemical Intermediate: A key synthon for the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl and dichloro motifs.
• Pharmaceutical Building Block: Used in medicinal chemistry for the synthesis of drug candidates, particularly in areas requiring enhanced lipophilicity and resistance to metabolic degradation.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic cores used in electronic display technologies and organic semiconductors.
• Polymer Modifier: Incorporated into specialty polymers to alter thermal stability, chemical resistance, and surface properties.
• Cross-Coupling Reactions: The carboxylic acid group allows for facile derivatization, making it a versatile substrate for Suzuki, Sonogashira, and other palladium-catalyzed couplings.
• Chemical Research & Development: Employed in academic and industrial labs for exploring new synthetic methodologies and creating novel chemical entities.

Basic Information

Product Name	4-Carboxy-3,5-Dichlorobenzotrifluoride
CAS No.	189338-32-7
Molecular Formula	C8H3Cl2F3O2
Molecular Weight	259.01 g/mol
Synonyms	3,5-Dichloro-4-(trifluoromethyl)benzoic Acid; 2,6-Dichloro-α,α,α-trifluoro-p-toluic Acid; 4-Carboxy-3,5-dichlorobenzotrifluoride; Benzoic acid, 3,5-dichloro-4-(trifluoromethyl)-; 3,5-Dichloro-α,α,α-trifluoro-p-toluic Acid
EINECS	Contact for details

Quality Control

Every batch of 4-Carboxy-3,5-Dichlorobenzotrifluoride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, and custom purity grades (e.g., >98%, >99%) are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.