Description

(R)-A-Hydroxy-3-Furanacetonitrile is a chiral furan derivative of significant interest in fine chemical synthesis. This compound serves as a versatile and valuable chiral building block for the production of complex pharmaceutical intermediates and active ingredients. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new therapeutic agents and high-value products.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its furan backbone for bioactive molecule construction.
• Asymmetric Catalysis Research: Serves as a standard or precursor in developing and testing new chiral catalysts and ligands for stereoselective reactions.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances where specific chirality is required.
• Academic & R&D: Utilized in university and corporate research laboratories for methodological studies in organic synthesis and medicinal chemistry.

Basic Information

Product Name	(R)-A-Hydroxy-3-Furanacetonitrile
CAS No.	188481-45-0
Molecular Formula	C7H7NO2
Molecular Weight	137.14 g/mol
Synonyms	(R)-2-(2-Furyl)-2-hydroxyacetonitrile; (R)-2-Hydroxy-2-(furan-2-yl)acetonitrile; (R)-α-Hydroxy-2-furanacetonitrile; (R)-2-Furylglycolonitrile; (R)-2-Hydroxy-2-(2-furyl)ethanenitrile; (R)-Furan-2-yl(hydroxy)acetonitrile; (2R)-2-Hydroxy-2-(furan-2-yl)acetonitrile
EINECS	Contact for details

Quality Control

Our (R)-A-Hydroxy-3-Furanacetonitrile is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to meet the stringent requirements of pharmaceutical R&D and production. A Certificate of Analysis (COA) detailing specific results for identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.