Description

n-Boc-D-Cyclohexylglycinol is a high-purity, chiral amino alcohol derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a protected amine and alcohol functionality, enabling the stereoselective construction of complex molecules with high fidelity. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs), peptide mimetics, and chiral catalysts.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, especially in protease inhibitor and antiviral research.
• Peptidomimetics Construction: Used to introduce the D-cyclohexylglycine moiety, a common non-natural amino acid surrogate, into peptide backbones to enhance metabolic stability and bioavailability.
• Asymmetric Synthesis: Employed as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce enantioselectivity.
• Custom Chemical Synthesis: Serves as a versatile starting material for contract research organizations (CROs) and CDMOs developing custom synthesis routes for clients.
• Agrochemical Research: Potential intermediate in the development of chiral active ingredients for crop protection agents.

Basic Information

Product Name	n-Boc-D-Cyclohexylglycinol
CAS No.	188348-00-7
Molecular Formula	C₁₃H₂₅NO₃
Molecular Weight	243.34 g/mol
Synonyms	(R)-2-((tert-Butoxycarbonyl)amino)-2-cyclohexyl-1-ethanol; (R)-2-((tert-Butoxycarbonyl)amino)-2-cyclohexylethanol; D-Cyclohexylglycinol, N-Boc-protected; (R)-N-Boc-2-Amino-2-cyclohexylethanol; Boc-D-Cyclohexylglycinol; tert-Butyl ((1R)-2-hydroxy-1-cyclohexylethyl)carbamate; (1R)-2-[(tert-Butoxycarbonyl)amino]-2-cyclohexyl-1-ethanol
EINECS	Contact for details

Quality Control

Our n-Boc-D-Cyclohexylglycinol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure compliance with stringent specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Single Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.