Description

Abacavir Sulfate CAS NO 188062-50-2 is the sulfate salt form of abacavir, a potent nucleoside reverse transcriptase inhibitor (NRTI). This high-purity active pharmaceutical ingredient (API) is critical for ensuring the efficacy and safety of antiviral medications. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of antiretroviral therapies for the treatment of HIV-1 infection.

Application

• Pharmaceutical API: Primary active ingredient in the formulation of antiretroviral tablets, oral solutions, and combination therapies for HIV treatment.
• Drug Substance Manufacturing: Serves as the key chemical entity in the synthesis and scale-up of finished dosage forms under GMP conditions.
• Research & Development: Used in preclinical and clinical studies for investigating new HIV treatment regimens, drug delivery systems, and combination therapies.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development, validation, and assay calibration.
• Generic Drug Production: Essential for manufacturers producing bioequivalent versions of branded antiretroviral medications containing abacavir.

Basic Information

Product Name	Abacavir Sulfate
CAS No.	188062-50-2
Molecular Formula	C14H18N6O · H2SO4
Molecular Weight	422.41 g/mol
Synonyms	Abacavir Sulphate; (1S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol sulfate; Ziagen Sulfate; ABC Sulfate; Abacavir Hemisulfate; Cyclopropavir Sulfate; GW 1592U89 Sulfate
EINECS	Contact for details

Quality Control

Our Abacavir Sulfate is manufactured and tested to meet stringent pharmacopeial standards, including USP and ICH guidelines. Every batch undergoes comprehensive analytical testing for identity, purity, potency, and specified impurities. A Certificate of Analysis (COA) detailing all test results is provided to ensure full traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.