Description

1,3:4,6-Di-o-Benzylidene-2,5-Dideoxy-2,5-Imino-L-Iditol is a high-purity, bicyclic iminosugar derivative that serves as a critical chiral building block and intermediate in advanced organic synthesis. Its unique, rigid structure makes it an invaluable scaffold for developing potent glycosidase inhibitors and carbohydrate-based pharmaceuticals. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors focused on metabolic disease therapeutics, antiviral agents, and novel chemical probes.

Application

• Pharmaceutical Intermediate: Key chiral precursor for the synthesis of potent glycosidase inhibitors targeting conditions like diabetes, Gaucher's disease, and viral infections.
• Biochemical Research: Used as a standard or tool compound in enzymology studies to investigate the mechanism and inhibition of specific glycosidases.
• Medicinal Chemistry: Serves as a privileged scaffold for structure-activity relationship (SAR) studies and the development of new drug candidates.
• Academic Synthesis: Employed in advanced organic chemistry laboratories for methodological development and the synthesis of complex, biologically active molecules.
• Process Chemistry: Utilized in the scale-up and optimization of synthetic routes for iminosugar-based active pharmaceutical ingredients (APIs).

Basic Information

Product Name	1,3:4,6-Di-o-Benzylidene-2,5-Dideoxy-2,5-Imino-L-Iditol
CAS No.	187343-15-3
Molecular Formula	C20H19NO4
Molecular Weight	337.37 g/mol
Synonyms	1,3:4,6-Di-O-benzylidene-2,5-dideoxy-2,5-imino-D-glucitol; (1R,2R,3S,4R,5S)-2,4-Dibenzylidene-3-hydroxy-1-(hydroxymethyl)-7-oxa-3-azabicyclo[3.2.1]octane; 2,5-Dideoxy-2,5-imino-1,3:4,6-di-O-benzylidene-L-iditol; DAB-1; L-Iditol derivative; Iminosugar benzylidene acetal; Bicyclic iminosugar acetal.
EINECS	Contact for details

Quality Control

Our 1,3:4,6-Di-o-Benzylidene-2,5-Dideoxy-2,5-Imino-L-Iditol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and structural confirmation via NMR and MS, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a desiccated environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.