Description

(3S,4S)-(-)-1-Benzyl-3,4-Dihydroxypyrrolidin-2,5-Dione is a high-purity chiral building block and synthetic intermediate of significant importance in asymmetric synthesis. This compound matters for its role as a key precursor in the development of pharmaceuticals and fine chemicals, enabling the construction of complex molecules with defined stereochemistry. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting neurological and metabolic disorders.
• Asymmetric Catalysis Ligand Precursor: Used in the development and synthesis of novel chiral ligands and organocatalysts for stereoselective transformations.
• Fine Chemical Synthesis: Serves as a versatile building block for creating complex natural product analogs and other high-value specialty chemicals.
• Agrochemical Research: Employed in the research and development of new chiral pesticides and herbicides with improved efficacy and selectivity.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry and for exploring new synthetic routes in process chemistry.

Basic Information

Product Name	(3S,4S)-(-)-1-Benzyl-3,4-Dihydroxypyrrolidin-2,5-Dione
CAS No.	187032-53-7
Molecular Formula	C11H11NO4
Molecular Weight	221.21 g/mol
Synonyms	(3S,4S)-1-Benzyl-3,4-dihydroxypyrrolidine-2,5-dione; (-)-1-Benzyl-3,4-dihydroxypyrrolidine-2,5-dione; (3S,4S)-1-Benzyl-3,4-dihydroxy-2,5-pyrrolidinedione; 1-Benzyl-3,4-dihydroxy-L-proline diketopiperazine derivative; Chiral benzyl pyrrolidinedione; (3S,4S)-BDP
EINECS	Contact for details

Quality Control

Our (3S,4S)-(-)-1-Benzyl-3,4-Dihydroxypyrrolidin-2,5-Dione is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for research and development applications. All products undergo rigorous analytical testing, including chiral HPLC and NMR, to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic nature, store under dry, inert conditions (e.g., nitrogen atmosphere) in a cool (15-25°C), dry place. Keep the container tightly sealed when not in use to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.