Description

3-(Benzyloxy)-5-Fluorobenzoic Acid is a high-purity fluorinated benzoic acid derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the strategic combination of a protected benzyloxy group and a fluorine atom, enabling precise structural modifications in complex molecule synthesis. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for constructing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic cores used in electronic display technologies.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development and exploring new fluorination chemistry pathways.
• Custom Synthesis & Contract Manufacturing: A vital substrate for fine chemical manufacturers producing bespoke compounds for client-specific projects.

Basic Information

Product Name	3-(Benzyloxy)-5-Fluorobenzoic Acid
CAS No.	186584-74-7
Molecular Formula	C14H11FO3
Molecular Weight	246.24 g/mol
Synonyms	5-Fluoro-3-(phenylmethoxy)benzoic Acid; Benzoic acid, 5-fluoro-3-(phenylmethoxy)-; 3-Benzyloxy-5-fluorobenzoic acid; 5-Fluoro-3-benzyloxybenzoic Acid; 186584-74-7; 3-(Benzyloxy)-5-fluorobenzoic acid; 3-(Phenylmethoxy)-5-fluorobenzoic acid
EINECS	Contact for details

Quality Control

Our production of 3-(Benzyloxy)-5-Fluorobenzoic Acid adheres to stringent quality management protocols. Each batch is analytically verified using advanced techniques including HPLC, GC, and NMR to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality system is designed to support cGMP compliance for pharmaceutical applications, ensuring traceability and reliability for our global B2B partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.