Description

3-Furancarboxylicacid,Tetrahydro-2,4-Dimethyl-5-Oxo-,[2S-(2Alpha,3Alpha,4Alpha)]-(9Ci) CAS NO 185246-58-6 is a high-purity, stereochemically defined chiral building block and synthetic intermediate. This compound is valued for its complex, functionalized tetrahydrofuran core, which is a privileged scaffold in medicinal chemistry and fine chemical synthesis. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly for compounds targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where its specific stereochemistry can influence biological activity and environmental fate.
• Fine Chemical Production: Acts as a versatile building block for synthesizing complex natural product analogs, flavors, and fragrances.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in academic and industrial research focused on developing new catalytic methodologies.
• Material Science Precursor: Potential use in the synthesis of specialized polymers or functional materials requiring specific molecular architectures.

Basic Information

Product Name	3-Furancarboxylicacid,Tetrahydro-2,4-Dimethyl-5-Oxo-,[2S-(2Alpha,3Alpha,4Alpha)]-(9Ci)
CAS No.	185246-58-6
Molecular Formula	C8H12O4
Molecular Weight	172.18 g/mol
Synonyms	(2S,3S,4S)-2,4-Dimethyl-5-oxotetrahydrofuran-3-carboxylic acid; (2S,3S,4S)-Tetrahydro-2,4-dimethyl-5-oxo-3-furancarboxylic acid; (2S,3S,4S)-5-Oxo-2,4-dimethyltetrahydrofuran-3-carboxylic acid; 3-Furancarboxylic acid, tetrahydro-2,4-dimethyl-5-oxo-, (2S,3S,4S)-; (2S,3S,4S)-2,4-Dimethyl-5-oxodihydro-2H-furan-3-carboxylic acid; (2S,3S,4S)-rel-2,4-Dimethyl-5-oxotetrahydro-3-furancarboxylic Acid; Chiral Tetrahydrofuran Carboxylic Acid Derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are available upon request. We adhere to a cGMP-compliant quality management system suitable for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.