Description

12-Thiocalanolide B is a specialized thiocalanolide derivative, a compound of significant interest in advanced organic synthesis and pharmaceutical research. Its unique sulfur-containing structure makes it a valuable intermediate for developing novel bioactive molecules and exploring structure-activity relationships. This high-purity compound is primarily utilized by research institutions and pharmaceutical development companies focused on medicinal chemistry and new chemical entity discovery.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold or precursor for exploring new chemical spaces and biological targets in drug discovery programs.
• Chemical Biology Probes: Employed in the development of molecular probes to study enzyme mechanisms and biological pathways.
• Process Chemistry Development: Acts as a critical intermediate for optimizing synthetic routes and scaling up production of complex molecules.
• Academic Research: Utilized in university and institutional labs for synthetic methodology development and heterocyclic chemistry studies.
• Reference Standard: Provides a high-purity standard for analytical method development, validation, and quality control in R&D settings.

Basic Information

Product Name	12-Thiocalanolide B
CAS No.	183791-90-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	12-Thiocalanolide B; Thiocalanolide B; 12-Sulfanylcalanolide B; 12-Mercaptocalanolide B; Calanolide B thio derivative; 12-Thiocalanolide; 183791-90-4; 12-Thio-calanolide B
EINECS	Contact for details

Quality Control

Our 12-Thiocalanolide B is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity analysis and structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results for identity, purity, and impurities. We support compliance with cGMP and ISO standards for research and development materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture and contamination. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%
Total Impurities	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.