Description

16(S)-Hete CAS NO 183509-23-1 is a high-purity, stereospecific hydroxyeicosatetraenoic acid (HETE) derivative, a significant bioactive lipid mediator. This compound is critical for researchers and developers in the life sciences sector, providing a precise tool for studying eicosanoid signaling pathways and their physiological roles. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and diagnostic manufacturers focused on inflammation, cardiovascular, and metabolic disease research.

Application

• Biochemical Research: Used as a reference standard and analytical reagent in the study of lipoxygenase pathways and eicosanoid biology.
• Pharmaceutical Development: Serves as a key intermediate or active pharmaceutical ingredient (API) precursor in the development of novel anti-inflammatory and cardioprotective agents.
• Diagnostic Assays: Employed as a calibrant or control in the development and validation of immunoassays (e.g., ELISA) and LC-MS/MS methods for quantifying lipid mediators.
• Cell Signaling Studies: Applied in in vitro and in vivo models to investigate receptor-ligand interactions and downstream cellular responses related to 16(S)-HETE.
• Metabolomics & Biomarker Discovery: A vital compound for profiling lipidomic signatures and identifying potential biomarkers in disease states.

Basic Information

Product Name	16(S)-Hete
CAS No.	183509-23-1
Molecular Formula	C₂₀H₃₂O₃
Molecular Weight	320.47 g/mol
Synonyms	16(S)-Hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic Acid; (16S)-HETE; 16S-HETE; 16(S)-HETE; 16S-Hydroxyeicosatetraenoic Acid; 16(S)-Hydroxyeicosatetraenoic Acid; 5Z,8Z,11Z,14Z-Eicosatetraenoic acid, 16-hydroxy-, (16S)-
EINECS	Contact for details

Quality Control

Every batch of 16(S)-Hete is manufactured and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing, including chiral purity verification, to ensure compliance with research and development standards. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided for each lot.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (IR / NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% (16S-isomer)
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.