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1-Oleoyl-2-Lauroyl -Sn-Glycero-3-Phosphocholine CAS NO 182294-04-8


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CAS No.:182294-04-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-Oleoyl-2-Lauroyl-sn-Glycero-3-Phosphocholine is a high-purity, synthetic phospholipid with a defined fatty acid chain composition. This compound is critical for creating stable, reproducible model membrane systems essential for biophysical research and pharmaceutical development. It is primarily needed by researchers and formulators in the life sciences, pharmaceutical, and cosmetic industries for applications ranging from liposome preparation to membrane protein studies.

Application

  • Liposome & Lipid Nanoparticle (LNP) Formulation: A key component for constructing stable, uniform vesicles for drug delivery systems, including mRNA vaccines and targeted cancer therapies.
  • Biophysical & Membrane Research: Used to create well-defined model membranes (e.g., supported lipid bilayers, vesicles) for studying membrane fluidity, protein-lipid interactions, and permeability.
  • Cell Culture & Transfection Reagents: Serves as a raw material in the production of lipid-based transfection reagents to introduce nucleic acids into cells.
  • Cosmetic & Dermal Delivery Systems: Employed in advanced cosmetic formulations to enhance the encapsulation and skin penetration of active ingredients.
  • Analytical Standards & Reference Materials: Provides a certified reference standard for quality control and analytical method development in lipidomics and related fields.
  • Biomimetic Coatings & Sensors: Used to develop sensor surfaces and biocompatible coatings that mimic natural cell membranes.

Basic Information

Product Name 1-Oleoyl-2-Lauroyl-sn-Glycero-3-Phosphocholine
CAS No. 182294-04-8
Molecular Formula C39H76NO8P
Molecular Weight 718.00 g/mol
Synonyms 18:1-12:0 PC; OLP-C; 1-Oleoyl-2-lauroyl-sn-glycero-3-phosphocholine; Phosphatidylcholine (18:1/12:0); PC(18:1/12:0); (2R)-2,3-Bis[[(Z)-octadec-9-enoyl]oxy]propyl 2-(trimethylazaniumyl)ethyl phosphate; 1-Oleoyl-2-lauroyl-phosphatidylcholine; Lauroyl Oleoyl Phosphatidyl Choline
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Quality Control

Our 1-Oleoyl-2-Lauroyl-sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and fatty acid profile confirmation, to ensure it meets the stringent requirements for research and formulation. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. Allow the product to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item Specification
Appearance White to off-white solid or waxy solid
Identification (IR & NMR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Fatty Acid Composition (GC) Oleic Acid (C18:1): 45-55%; Lauric Acid (C12:0): 45-55%
Solvent Content (Residual Solvents) Meet ICH guidelines
Water Content (KF) ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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