Description

1-(3-Fluorophenyl)Cyclobutanecarboxylic Acid is a high-purity fluorinated cyclobutane derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in the unique structural combination of the cyclobutane ring and a fluorinated aromatic system, which is instrumental for modulating the physicochemical properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and complex organic frameworks.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides, where the fluorine atom enhances bioactivity and environmental stability.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers, liquid crystals, and advanced organic electronic materials.
• Chemical Biology & Proteomics: Employed as a molecular probe or a tag precursor in activity-based protein profiling (ABPP) and bioconjugation strategies.
• Academic & Contract Research: A valuable reagent for methodological studies in organic synthesis, including ring-opening, cross-coupling, and fluorination chemistry.
• Custom Synthesis & Scale-Up: Provides a reliable starting point for contract manufacturing organizations (CMOs) and fine chemical suppliers for custom synthesis projects from gram to kilogram scale.

Basic Information

Product Name	1-(3-Fluorophenyl)Cyclobutanecarboxylic Acid
CAS No.	179411-84-8
Molecular Formula	C11H11FO2
Molecular Weight	194.20 g/mol
Synonyms	3-Fluorophenylcyclobutanecarboxylic Acid; 1-(3-Fluorophenyl)cyclobutane-1-carboxylic Acid; Cyclobutanecarboxylic acid, 1-(3-fluorophenyl)-; 3-Fluorophenyl-1-cyclobutanecarboxylic Acid; 1-(m-Fluorophenyl)cyclobutanecarboxylic Acid; 179411-84-8; FCBCA
EINECS	Contact for details

Quality Control

Every batch of 1-(3-Fluorophenyl)Cyclobutanecarboxylic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We ensure compliance with stringent in-house specifications developed for advanced intermediates. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles. Our quality commitment extends to supporting regulatory filings with consistent, well-documented material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.