Description

3-Pyrrolidinamine, 1-(Trifluoroacetyl)-, (S)- (9Ci) is a high-value, chiral pyrrolidine derivative featuring a trifluoroacetyl protecting group. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, enabling the introduction of a stereodefined pyrrolidine scaffold. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs), ligands, and complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Asymmetric Synthesis: Employed as a chiral auxiliary or precursor to chiral catalysts and ligands in stereoselective transformations.
• Agrochemical Research: Used in the synthesis of advanced crop protection agents and pesticides requiring specific stereochemistry for optimal activity.
• Chemical Biology & Medicinal Chemistry: Integral for constructing molecular probes and libraries to study biological pathways and structure-activity relationships (SAR).
• Process Chemistry & Scale-up: Serves as a starting material for the pilot and commercial-scale manufacturing of optically active compounds.
• Academic & Contract Research: A valuable reagent for methodology development and complex molecule synthesis in academic and industrial R&D laboratories.

Basic Information

Item	Details
Product Name	3-Pyrrolidinamine, 1-(Trifluoroacetyl)-, (S)- (9Ci)
CAS No.	178688-08-9
Molecular Formula	C6H9F3N2O
Molecular Weight	182.15 g/mol
Synonyms	(S)-1-(Trifluoroacetyl)-3-pyrrolidinamine; (S)-3-Amino-1-(trifluoroacetyl)pyrrolidine; (S)-N-(Trifluoroacetyl)-3-aminopyrrolidine; (S)-1-Trifluoroacetyl-3-aminopyrrolidine; (S)-3-Pyrrolidinamine, 1-(trifluoroacetyl)-; (S)-3-Aminopyrrolidine-1-carboxylic acid trifluoroacetic anhydride derivative; (S)-TFA-3-aminopyrrolidine
EINECS	Contact for details

Quality Control

Our 3-Pyrrolidinamine, 1-(Trifluoroacetyl)-, (S)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep away from incompatible materials such as strong bases and fluorides.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.