Description

3',5'-Di-(Trifluoromethyl)-Biphenyl-3-Carboxylic Acid is a high-purity, multi-functional aromatic carboxylic acid derivative, distinguished by its strategically positioned trifluoromethyl groups. This compound is a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern organic synthesis, prized for its ability to impart unique electronic and steric properties to target molecules. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and specialty materials sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, anti-inflammatory agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the trifluoromethyl groups enhance biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating sophisticated ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of monomers for specialty polymers, liquid crystals, and organic electronic materials due to its rigid biphenyl core and fluorine content.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, quality control, and regulatory compliance in laboratory settings.

Basic Information

Product Name	3',5'-Di-(Trifluoromethyl)-Biphenyl-3-Carboxylic Acid
CAS No.	177733-57-2
Molecular Formula	C15H8F6O2
Molecular Weight	334.22 g/mol
Synonyms	[3',5'-Bis(trifluoromethyl)[1,1'-biphenyl]-3-carboxylic acid; 3-(3,5-Bis(trifluoromethyl)phenyl)benzoic acid; Biphenyl-3-carboxylic acid, 3',5'-bis(trifluoromethyl)-; 3',5'-Di(trifluoromethyl)biphenyl-3-carboxylic acid; 3-Carboxy-3',5'-bis(trifluoromethyl)biphenyl]
EINECS	Contact for details

Quality Control

Our production of 3',5'-Di-(Trifluoromethyl)-Biphenyl-3-Carboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to cGMP principles and reliable supply chain integrity makes us a trusted partner for critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.