Description

4-Chloro-2-Fluoro-5-Methylbenzoic Acid is a high-purity, multi-functional benzoic acid derivative distinguished by its specific halogen substitution pattern. This compound serves as a critical pharmaceutical intermediate and agrochemical building block, enabling the synthesis of advanced active ingredients. It is essential for R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of herbicides, fungicides, and novel drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the chloro-fluoro-methyl substitution offers specific bioactivity and stability.
• Liquid Crystal Material Precursor: Serves as an intermediate in the manufacture of fluorinated liquid crystals for display technologies.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce functionalized benzoic acid moieties into complex molecules.
• Polymer Modifier: Used to synthesize monomers for specialty polymers, imparting specific chemical resistance or thermal properties.
• Research & Development: A valuable compound for medicinal chemistry and material science research exploring structure-activity relationships.

Basic Information

Product Name	4-Chloro-2-Fluoro-5-Methylbenzoic Acid
CAS No.	177211-31-3
Molecular Formula	C8H6ClFO2
Molecular Weight	188.58 g/mol
Synonyms	5-Methyl-4-chloro-2-fluorobenzoic Acid; 4-Chloro-2-fluoro-5-methyl-benzoic Acid; 2-Fluoro-4-chloro-5-methylbenzoic Acid; Benzoic acid, 4-chloro-2-fluoro-5-methyl-; 177211-31-3; 4-Chloro-2-fluoro-5-methylbenzoic acid; 4-Chloro-2-fluoro-5-methylbenzoicacid
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Fluoro-5-Methylbenzoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤0.5%
Related Substances (HPLC)	Total impurities ≤2.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.