Description

4-Chloro-3-(Trifluoromethyl)Phenylboronic Acid is a high-purity organoboron compound serving as a critical building block in modern synthetic chemistry. Its value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone method for constructing complex biaryl and heterobiaryl structures. This boronic acid is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing trifluoromethyl and chloro-substituted biphenyl motifs.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the specific halogenated aromatic structure imparts desired biological activity and stability.
• Material Science: Building block for organic electronic materials, such as those used in OLEDs and organic photovoltaics, where its structure aids in tuning electronic properties.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new carbon-carbon bond-forming methodologies and creating compound libraries.
• Liquid Crystal & Polymer Chemistry: Intermediate in the production of specialty monomers and polymers designed for high-performance applications.

Basic Information

Product Name	4-Chloro-3-(Trifluoromethyl)Phenylboronic Acid
CAS No.	176976-42-4
Molecular Formula	C7H5BClF3O2
Molecular Weight	223.37 g/mol
Synonyms	4-Chloro-3-(trifluoromethyl)benzeneboronic acid; [4-Chloro-3-(trifluoromethyl)phenyl]boronic acid; 2-Chloro-α,α,α-trifluoro-m-tolylboronic acid; (4-Chloro-3-trifluoromethylphenyl)boronic acid; B-[4-Chloro-3-(trifluoromethyl)phenyl]boronic acid; 4-Chloro-α,α,α-trifluoro-m-tolylboronic acid; 176976-42-4; Boronic acid, B-[4-chloro-3-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-(Trifluoromethyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance for demanding synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.