Description

n-(tert-Butyloxy)Carbonyl Anthranilic Acid-13C6 is a stable isotope-labeled derivative of anthranilic acid, where the aromatic ring is uniformly labeled with carbon-13. This compound is a critical building block for the synthesis of isotopically labeled peptides, pharmaceuticals, and advanced organic materials, enabling precise metabolic and pharmacokinetic studies. It is primarily utilized by research institutions, pharmaceutical development laboratories, and specialty chemical manufacturers engaged in tracer analysis, quantitative proteomics, and the development of novel diagnostic agents.

Application

• Isotopic Tracer Synthesis: Serves as a key precursor for incorporating carbon-13 labels into complex molecules for metabolic pathway analysis and drug metabolism studies (ADME).
• Pharmaceutical Research: Used in the development and validation of quantitative bioanalytical methods, such as LC-MS/MS, where it acts as an internal standard for accurate quantification.
• Peptide Chemistry: Functions as a protected, labeled amino acid derivative for the solid-phase and solution-phase synthesis of isotopically labeled peptides.
• Advanced Material Development: Employed in the creation of labeled polymers or organic semiconductors for research into material properties and degradation pathways.
• Regulatory & Safety Testing: Essential for conducting definitive environmental fate studies and residue analysis in compliance with global regulatory standards.

Basic Information

Product Name	n-(tert-Butyloxy)Carbonyl Anthranilic Acid-13C6
CAS No.	176850-22-9
Molecular Formula	C1213C6H15NO4
Molecular Weight	~279.2 (for 13C6 labeled form)
Synonyms	Boc-Anthranilic Acid-13C6; 2-[[(1,1-Dimethylethoxy)carbonyl]amino]benzoic Acid-13C6; N-Boc-anthranilic Acid-13C6; Boc-2-Aminobenzoic Acid-13C6; (Boc)2O-Anthranilic Acid-13C6; tert-Butyl Anthranilate-N-carboxylate-13C6; N-tert-Butoxycarbonyl Anthranilic Acid-13C6
EINECS	Contact for details

Quality Control

Our n-(tert-Butyloxy)Carbonyl Anthranilic Acid-13C6 is manufactured under strict quality systems to ensure high isotopic and chemical purity, critical for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment (Atom % 13C), chemical purity by HPLC, and identity confirmation by NMR and MS. We adhere to relevant guidelines for the production of labeled compounds for research use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after opening to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (Atom % 13C)	≥ 99% on labeled positions
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.