Description

(2R,5R)-(+)-Bis(Diphenylphosphino)Hexane is a high-purity, chiral bidentate phosphine ligand essential for asymmetric catalysis. Its value lies in enabling highly enantioselective transformations, critical for producing single-isomer pharmaceuticals and fine chemicals. This product is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel synthetic routes.

Application

• Asymmetric Hydrogenation: A key ligand for the enantioselective reduction of prochiral olefins, enamines, and ketones in API synthesis.
• Cross-Coupling Reactions: Facilitates asymmetric versions of Suzuki, Heck, and other C-C bond-forming reactions.
• Pharmaceutical Intermediate Synthesis: Used in the production of chiral active pharmaceutical ingredients (APIs) and key intermediates.
• Agrochemical Manufacturing: Applied in the synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Academic & Industrial R&D: Serves as a critical tool for developing new catalytic methodologies and exploring novel chemical space.
• Fine Chemical Production: Enables the commercial-scale manufacture of specialty flavors, fragrances, and electronic chemicals with high optical purity.

Basic Information

Product Name	(2R,5R)-(+)-Bis(Diphenylphosphino)Hexane
CAS No.	175892-81-6
Molecular Formula	C30H32P2
Molecular Weight	454.52 g/mol
Synonyms	(2R,5R)-1,2-Bis(diphenylphosphino)hexane; (R,R)-BDPH; (2R,5R)-BDPH; (R,R)-1,2-Bis(diphenylphosphino)hexane; (+)-(R,R)-Bis(diphenylphosphino)hexane; (R,R)-(-)-1,2-Bis(diphenylphosphino)hexane; DuPhos hexane ligand; ChiraPhos
EINECS	Contact for details

Quality Control

Our (2R,5R)-(+)-Bis(Diphenylphosphino)Hexane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC and 31P NMR spectroscopy, to ensure it meets the high standards required for sensitive catalytic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store under an inert atmosphere (argon or nitrogen) at 2-8°C. This compound is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (ee)	≥ 99.0%
Melting Point	Contact for details
Specific Rotation [α]	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.