Description

2-(Trifluoromethoxy)Benzoic Acid Hydrazide is a high-purity, specialized organic intermediate featuring a reactive hydrazide group and a trifluoromethoxy substituent. This unique structure makes it a critical building block for synthesizing novel compounds with enhanced biological activity and physicochemical properties. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for creating new active ingredients, as well as by fine chemical manufacturers producing advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobials.
• Agrochemical Synthesis: Used to develop advanced herbicides, fungicides, and insecticides where the trifluoromethoxy group can improve metabolic stability and lipophilicity.
• Ligand and Chelator Preparation: Serves as a starting material for creating specialized ligands used in catalysis and metal complexation.
• Polymer Modification: Employed to introduce functional hydrazide groups into polymer chains for cross-linking or to impart specific material properties.
• Chemical Research & Development: A versatile scaffold in medicinal and synthetic chemistry for constructing heterocyclic compounds like pyrazoles, triazoles, and oxadiazoles.
• Advanced Material Production: Used in the development of liquid crystals, organic semiconductors, and other performance materials.

Basic Information

Product Name	2-(Trifluoromethoxy)Benzoic Acid Hydrazide
CAS No.	175277-19-7
Molecular Formula	C8H7F3N2O2
Molecular Weight	220.15 g/mol
Synonyms	2-(Trifluoromethoxy)benzohydrazide; o-(Trifluoromethoxy)benzoic acid hydrazide; Benzoic acid, 2-(trifluoromethoxy)-, hydrazide; 2-(Trifluoromethoxy)benzoyl hydrazine; [2-(Trifluoromethoxy)phenyl]carbohydrazide; α,α,α-Trifluoro-o-anisic acid hydrazide; 2-(Trifluoromethoxy)benzhydrazide
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethoxy)Benzoic Acid Hydrazide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.