Description

trans-2-(3-Fluoro-Phenyl)-Cyclopropanecarboxylic Acid is a high-purity, fluorinated cyclopropane derivative that serves as a critical chiral building block in advanced organic synthesis. Its unique structural motif, combining a cyclopropane ring with a fluorinated aromatic system, makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atom and cyclopropane ring can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials that require fluorinated aromatic components.
• Chemical Biology Probes: Useful for constructing molecular probes to study enzyme mechanisms and biological pathways due to its structural rigidity and fluorine label.

Basic Information

Product Name	trans-2-(3-Fluoro-Phenyl)-Cyclopropanecarboxylic Acid
CAS No.	175168-72-6
Molecular Formula	C10H9FO2
Molecular Weight	180.18 g/mol
Synonyms	(1R,2S)-2-(3-Fluorophenyl)cyclopropanecarboxylic Acid; (1S,2R)-2-(3-Fluorophenyl)cyclopropanecarboxylic Acid; trans-2-(m-Fluorophenyl)cyclopropanecarboxylic Acid; 2-(3-Fluorophenyl)cyclopropanecarboxylic Acid; 3-Fluorophenylcyclopropanecarboxylic Acid; (1R,2S)-rel-2-(3-Fluorophenyl)cyclopropanecarboxylic Acid; 175168-72-6
EINECS	Contact for details

Quality Control

Our trans-2-(3-Fluoro-Phenyl)-Cyclopropanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.