Description

Bevirimat CAS NO 174022-42-5 is a potent and specific maturation inhibitor that targets the HIV-1 Gag protein. This compound is of significant interest for its role in novel antiretroviral therapeutic strategies, offering a mechanism of action distinct from other classes of HIV drugs. It is primarily utilized by pharmaceutical research and development organizations, contract research organizations (CROs), and academic institutions engaged in virology and infectious disease research.

Application

• Antiviral Research: A key reference standard and active compound in the study of HIV-1 maturation inhibition mechanisms.
• Pharmaceutical Development: Serves as a critical intermediate or active pharmaceutical ingredient (API) in the preclinical and clinical development of next-generation HIV therapies.
• Biochemical Assays: Used in high-throughput screening (HTS) and in vitro assays to evaluate antiviral activity and resistance profiles.
• Virology Studies: Employed as a tool compound to investigate the late stages of the HIV-1 replication cycle and capsid assembly.
• Drug Combination Studies: Research into synergistic effects with other antiretroviral agents to develop improved treatment regimens.

Basic Information

Product Name	Bevirimat
CAS No.	174022-42-5
Molecular Formula	C₃₆H₅₆O₅
Molecular Weight	568.8 g/mol
Synonyms	PA-457; MPC-4326; 3-O-(3',3'-Dimethylsuccinyl)betulinic acid; DSB; Bevirimat Dimethyl Succinate; (3β)-3-(3-Carboxy-3-methyl-1-oxobutoxy)lup-20(29)-en-28-oic acid
EINECS	Contact for details

Quality Control

Our Bevirimat is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We ensure compliance with relevant standards for research-grade chemicals, supporting your critical work in drug discovery.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.