Description

(R)-(+)-2,2'-Bis(Methoxymethoxy)-1,1'-Binaphthyl is a high-value chiral ligand and synthetic intermediate, recognized for its pivotal role in asymmetric catalysis. Its core value lies in enabling the production of enantiomerically pure compounds, which are critical for the efficacy and safety of advanced pharmaceuticals and specialty chemicals. This product is essential for research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors who require precise stereochemical control in their synthetic processes.

Application

• Asymmetric Catalysis: Serves as a privileged chiral ligand or precursor for ligands in transition-metal-catalyzed reactions such as hydrogenation, C-C bond formation, and oxidation.
• Pharmaceutical Intermediate: A key building block in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) for drugs targeting central nervous system disorders, cardiovascular diseases, and infections.
• Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides to enhance biological activity and reduce environmental impact.
• Material Science: Employed in the synthesis of chiral polymers and liquid crystals for advanced optical and electronic materials.
• Academic & Industrial R&D: A fundamental tool for method development and discovery chemistry in laboratories focused on stereoselective synthesis.

Basic Information

Product Name	(R)-(+)-2,2'-Bis(Methoxymethoxy)-1,1'-Binaphthyl
CAS No.	173831-50-0
Molecular Formula	C₂₄H₂₂O₄
Molecular Weight	374.43 g/mol
Synonyms	(R)-(+)-BINOL-DMOM; (R)-2,2'-Bis(methoxymethoxy)-1,1'-binaphthyl; (R)-DMOM-BINOL; (R)-(+)-1,1'-Bi-2-naphthol Dimethyl Ether; (R)-1,1'-Binaphthalene-2,2'-diyl bis(methoxymethyl) ether; (R)-2,2'-Di(methoxymethoxy)-1,1'-binaphthyl; (R)-BINOL bis(methyl ether) derivative
EINECS	Contact for details

Quality Control

Our (R)-(+)-2,2'-Bis(Methoxymethoxy)-1,1'-Binaphthyl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets the high standards required for sensitive asymmetric synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and residual solvent levels is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light) and should be handled under an inert atmosphere when appropriate for prolonged use to maintain optimal stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.