Description

Lamivudine Salicylate is a pharmaceutically relevant salt form of the potent nucleoside reverse transcriptase inhibitor, Lamivudine. This specific salt formation is critical for enhancing the stability, solubility, and overall pharmacokinetic profile of the active pharmaceutical ingredient (API). It is primarily utilized in the research, development, and manufacturing of advanced antiviral therapeutics, offering a reliable solution for formulators seeking consistent quality and performance.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of finished dosage forms of Lamivudine-based medications.
• Antiviral Drug Development: Used in R&D for creating and testing new formulations targeting HIV-1, HIV-2, and Hepatitis B virus.
• Reference Standard: Acts as a high-purity standard for analytical testing, quality control, and regulatory submissions in pharmaceutical laboratories.
• API Manufacturing: Incorporated into the production process of the final Active Pharmaceutical Ingredient (API) under controlled GMP environments.
• Biochemical Research: Employed in virology and molecular biology studies to investigate mechanisms of viral inhibition.
• Formulation Optimization: Utilized to improve drug stability, bioavailability, and patient compliance in solid and liquid dosage forms.

Basic Information

Product Name	Lamivudine Salicylate
CAS No.	173522-96-8
Molecular Formula	C16H21N3O6S
Molecular Weight	383.42 g/mol
Synonyms	Lamivudine 2-Hydroxybenzoate; 4-Amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-1,2-dihydro-2-pyrimidinone Salicylate; (-)-2'-Deoxy-3'-thiacytidine Salicylate; 3TC Salicylate; BCH-189 Salicylate; GR-109714X Salicylate; Epivir Intermediate Salicylate Salt
EINECS	Contact for details

Quality Control

Our Lamivudine Salicylate is manufactured and tested to meet stringent quality standards suitable for pharmaceutical applications. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identification by spectroscopic methods, and control of residual solvents and related substances. A Certificate of Analysis (COA) is provided with each shipment, detailing all specifications and test results to ensure traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.